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Article

Regulation of cellular growth by the Drosophila target of rapamycin dTOR.

Genes & development - 1 Nov 2000

Zhang H, Stallock J P, Ng J C, Reinhard C, Neufeld T P

Abstract excerpt

The TOR protein kinases (TOR1 and TOR2 in yeast; mTOR/FRAP/RAFT1 in mammals) promote cellular proliferation in response to nutrients and growth factors, but their role in development is poorly understood. Here, we show that the Drosophila TOR homolog dTOR is required cell autonomously for normal growth and proliferation during larval development, and for increases in cellular growth caused by activation of the...

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Identifiers

PMID: 11069888
DOI: 10.1101/gad.835000
PMCID: PMC317034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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