Article
Association of interleukin-I beta and receptor antagonist gene polymorphisms with late onset Alzheimer's disease in Taiwan Chinese.
European journal of neurology - 1 Aug 2005
Wang W-F, Liao Y-C, Wu S-L, Tsai F-J, Lee C-C, Hua C-S
Abstract excerpt
Interleukin (IL)-1 is markedly overexpressed in the brains of patients with Alzheimer's disease (AD). We aimed to evaluate the relationship between three polymorphisms of the IL1 gene (IL-1beta promoter -511T/C, IL-1beta exon 5 E1/E2 and IL-1-RA) and late onset AD in Taiwan Chinese. Forty-six late onset AD patients and 103 unrelated, age-matched, healthy controls living in the same area were included. PCR was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.