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Article

Functional analysis of CaIPT1, a sphingolipid biosynthetic gene involved in multidrug resistance and morphogenesis of Candida albicans.

Antimicrobial agents and chemotherapy - 1 Aug 2005

Prasad Tulika, Saini Preeti, Gaur Naseem Akhtar, Vishwakarma Ram A, Khan Luqman Ahmad, Haq Qazi M Rizwanul, Prasad Rajendra

Abstract excerpt

In the present study we describe the isolation and functional analysis of a sphingolipid biosynthetic gene, IPT1, of Candida albicans. The functional consequence of the disruption of both alleles of IPT1 was confirmed by mass analysis of its sphingolipid composition. The disruption of both allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16048959
DOI: 10.1128/AAC.49.8.3442-3452.2005
PMCID: PMC1196211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16048959-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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