Article
Hangover susceptibility in relation to aldehyde dehydrogenase-2 genotype, alcohol flushing, and mean corpuscular volume in Japanese workers.
Alcoholism, clinical and experimental research - 1 Jul 2005
Yokoyama Masako, Yokoyama Akira, Yokoyama Tetsuji, Funazu Kazuo, Hamana Genichi, Kondo Shuji, Yamashita Takeshi, Nakamura Haruo
Abstract excerpt
BACKGROUND: A study of Asian-American students suggested a positive association between inactive ALDH2*2 and susceptibility to hangover. A biomarker for moderate-to-heavy drinking in persons with inactive aldehyde dehydrogenase-2 (ALDH2) is increased mean corpuscular volume (MCV). METHODS: Associations between hangover and ALDH2 genotype, alcohol flushing, and MCV were examined for 251 Japanese workers (139 men,...
Topics
- Adult
- Alcohol Drinking
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Alleles
- Asian People
- DNA Mutational Analysis
- Enzyme Activation
- Erythrocyte Indices
- Female
- Flushing
- Genetic Carrier Screening