Article
Variability of CYP3A7 expression in human fetal liver.
The Journal of pharmacology and experimental therapeutics - 1 Aug 2005
Leeder J Steven, Gaedigk Roger, Marcucci Kenda A, Gaedigk Andrea, Vyhlidal Carrie A, Schindel Bradley P, Pearce Robin E
Abstract excerpt
Fetal liver CYP3A7 plays an important role in placental estriol synthesis during pregnancy, yet little is known concerning the extent or consequences of variability in expression. The purpose of this investigation was to characterize the variability in CYP3A7 expression using several phenotypic measures in a panel of 54 fetal livers ranging in age from 76 days to 32 weeks gestation. CYP3A7 mRNA expression was...
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