Article
TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis.
Developmental biology - 1 Sept 2005
Indra Arup Kumar, Mohan William S, Frontini Mattia, Scheer Elisabeth, Messaddeq Nadia, Metzger Daniel, Tora Làszlò
Abstract excerpt
TFIID, composed of the TATA box binding protein (TBP) and 13 TBP-associated factors (TAFs), plays a role in nucleating the assembly of the RNA polymerase II preinitiation complexes on protein coding genes. TAF10 (formerly TAF(II)30) is shared between TFIID and other transcription regulatory complexes (i.e. SAGA, TFTC, STAGA and PCAF/GCN5). TAF10 is an essential transcription factor during very early stages of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
