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Article

Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation.

The Journal of investigative dermatology - 1 Jun 2009

Golonzhka Olga, Liang Xiaobo, Messaddeq Nadia, Bornert Jean-Marc, Campbell Adam L, Metzger Daniel, Chambon Pierre, Ganguli-Indra Gitali, Leid Mark, Indra Arup K

Abstract excerpt

COUP-TF-interacting protein 2 (CTIP2; also known as Bcl11b) is a transcription factor that plays key roles in the development of the central nervous and immune systems. CTIP2 is also highly expressed in the developing epidermis, and at lower levels in the dermis and in adult skin. Analyses of mice harboring a germline deletion of CTIP2 revealed that the protein plays critical roles in skin during development,...

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Identifiers

PMID: 19092943
DOI: 10.1038/jid.2008.392
PMCID: PMC2754722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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