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Article

Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13.

Immunity - 1 Jul 2005

Guo Liying, Hu-Li Jane, Paul William E

Abstract excerpt

Il4 and Il13, closely linked genes, are expressed monoallelically in TH2 cells. Four different approaches (RNA FISH, cultures from Il13T-Il4/Il13-G4 mice, cultures from heterozygous Il13-Il4 double knockout mice, and a highly selected set of BABL/c*CAST/Ei clones displaying strong Il4 allelic bias) were utilized to study monoallelic expression of Il4 and coexpression of Il4 and Il13 on the same chromosome. There...

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PMID: 16039582
DOI: 10.1016/j.immuni.2005.05.008

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CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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