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Article

The Cell Type-Specific Expression of the Murine <i>IL-13</i> Gene Is Regulated by GATA-3

1 Oct 2001

Abstract excerpt

IL-13, a Th2 cell-specific cytokine, is a major effector molecule mediating several pathological features of allergic asthma. However, the transcriptional regulation of the IL-13 gene remains unclear. Here we demonstrate, by using intracellular cytokine staining, that IL-13 is not always coexpressed with other Th2 cytokines in normal Th cells on a single cell basis. In addition, we identified and cloned a minimal...

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PMID: 11591766
DOI: 10.4049/jimmunol.167.8.4414

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The Cell Type-Specific Expression of the Murine <i>IL-13</i> Gene Is Regulated by GATA-3PMID 11591766Read ↗

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