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Article

Genetic association analysis of neuronal nitric oxide synthase gene polymorphism with tardive dyskinesia.

Neuromolecular medicine - 1 Jan 2004

Shinkai Takahiro, Ohmori Osamu, Matsumoto Chima, Hori Hiroko, Kennedy James L, Nakamura Jun

Abstract excerpt

Possible involvement of oxidative stress in the pathophysiology of tardive dyskinesia (TD) has been proposed. Long-term administration of neuroleptics alters dopaminergic turnover, yielding the increase of the formation of reactive oxygen species (ROS), which may lead to TD through neuronal toxicity as a consequence of oxidative stress. In the present study, the relationship between TD and a polymorphism of the...

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Source

Identifiers

PMID: 15075442
DOI: 10.1385/NMM:5:2:163

Genes

NOS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association analysis of neuronal nitric oxide synthase gene polymorphism with tardive dyskinesia.PMID 15075442Read ↗

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