No association between a functional NAD(P)H: quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia.

doi:10.1385/NMM:8:3:375

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Article

No association between a functional NAD(P)H: quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia.

Neuromolecular medicine - 1 Jan 2006

Hori Hiroko, Shinkai Takahiro, Matsumoto Chima, Ohmori Osamu, Nakamura Jun

Abstract excerpt

Several lines of evidence have indicated that free radicals may play a role in the pathophysiology of tardive dyskinesia (TD) (reviewed in Andreassen and Jorgensen, 2000). NAD(P)H: quinone oxidoreductase (NQO1) is an important enzyme in the human body that counteracts the oxidative stress-induced...

Topics

Adult
Aged
Dyskinesias
Female
Genetic Predisposition to Disease
Genotype
Humans
Japan
Male
Middle Aged
NAD(P)H Dehydrogenase (Quinone)
NADP
Polymorphism, Genetic
Risk Factors

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