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Article

The application of real-time PCR to the analysis of T cell repertoires.

Nucleic acids research - 1 Dec 2008

Wettstein Peter, Strausbauch Michael, Therneau Terry, Borson Nancy

Abstract excerpt

The diversity of T-cell populations is determined by the spectrum of antigen-specific T-cell receptors (TCRs) that are heterodimers of alpha and beta subunits encoded by rearranged combinations of variable (AV and BV), joining (AJ and BJ), and constant region genes (AC and BC). We have developed a novel approach for analysis of beta transcript diversity in mice with a real-time PCR-based method that uses a matrix...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell, alpha-beta

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Source

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Identifiers

PMID: 18835849
DOI: 10.1093/nar/gkn634
PMCID: PMC2588499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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