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Increased expression of interleukin-6 gene in gastritis and gastric cancer

1 Jan 2021

Abstract excerpt

Helicobacter pylori (H. pylori) induces an intense inflammatory response, mediated by proinflammatory cytokines, including interleukin (IL)-6 and its membrane receptor (IL-6R), which activates important signaling pathways in the development of gastric disease and cancer. We investigated the gene and protein expression of IL-6 and IL-6R and the influence of polymorphisms rs1800795, rs1800796, and rs1800797 on its...

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PMID: 34008757
DOI: 10.1590/1414-431x2020e10687

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