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Article

In vivo phenotypic dominance in mouse mixed infections with Mycobacterium tuberculosis clinical isolates.

The Journal of infectious diseases - 15 Aug 2005

Barczak Amy K, Domenech Pilar, Boshoff Helena I M, Reed Michael B, Manca Claudia, Kaplan Gilla, Barry Clifton E

Abstract excerpt

Clinical isolates of Mycobacterium tuberculosis demonstrate significant heterogeneity in virulence potential in animal models of infection. Isolate CDC1551, for example, has previously been described in mouse survival studies as being hypovirulent, and isolate HN878 has been described as being hypervirulent. Observed differences in this mouse infection experiment have been proposed to reflect differential...

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PMID: 16028128
DOI: 10.1086/432006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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