Article
Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.
Histochemistry and cell biology - 1 Jul 2005
Van Schoore Grégory, Mendive Fernando, Pochet Roland, Vassart Gilbert
Abstract excerpt
Leucine-rich G-protein-coupled Receptors (LGR) constitute a subfamily of receptors related to glycoprotein hormone receptors. Amongst them, LGR4, LGR5 and LGR6 form a cluster for which natural agonists are still unknown. By an extensive gene trapping approach, Leighton et al. (2001) obtained a mouse line in which the LGR4 gene is disrupted by a trap vector carrying two biological markers, beta-geo (a fusion...
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