Article
Defective postnatal development of the male reproductive tract in LGR4 knockout mice.
Developmental biology - 15 Feb 2006
Mendive Fernando, Laurent Patrick, Van Schoore Grégory, Skarnes William, Pochet Roland, Vassart Gilbert
Abstract excerpt
The final outcome of tube elongation and branching is to maximize the epithelial exchange surfaces in tubular organs. The molecular and cellular basis of these processes is actively studied in model organs such as mammary glands, liver and kidney, but they remain almost unexplored in the male reproductive tract. Here, we report that the orphan G protein-coupled receptor LGR4/GPR48 plays a role in the postnatal...
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