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Article

A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus.

Proceedings of the National Academy of Sciences of the United States of America - 26 Jul 2005

Hawn Thomas R, Wu Hui, Grossman Jennifer M, Hahn Bevra H, Tsao Betty P, Aderem Alan

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease with a complex genetic basis that includes susceptibility gene(s) within the chromosome 1q41-1q42 region. Toll-like receptor 5 (TLR5), the innate immune receptor for bacterial flagellin, maps to chromosome 1q41 and contains a common stop...

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Source

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Identifiers

PMID: 16027372
DOI: 10.1073/pnas.0501165102
PMCID: PMC1180760

Genes

TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16027372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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