Article
Intracellular processing of the paramyxovirus F protein: critical role of the predicted amphipathic alpha helix adjacent to the fusion domain.
Journal of virology - 1 Jul 1992
Wang C, Raghu G, Morrison T, Peeples M E
Abstract excerpt
At a nonpermissive temperature, the group D temperature-sensitive mutants of Newcastle disease virus strain Australia-Victoria (AV) are defective in plaque formation, in inducing infected cells to fuse, and in incorporating the cleaved fusion glycoprotein, F1 + F2, into virus particles. In this s...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Transport
- Chick Embryo
- DNA, Viral
- Genetic Complementation Test
- Giant Cells
- Molecular Sequence Data
- Mutation
- Newcastle disease virus
- Protein Conformation
- Protein Processing, Post-Translational
- RNA, Viral
- Sequence Alignment
- Viral Fusion Proteins
- Viral Matrix Proteins
- Viral Plaque Assay