Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of the Fusion and Hemagglutinin-Neuraminidase Proteins in Replication, Tropism, and Pathogenicity of Avian Paramyxoviruses

17 Jun 2011

Abstract excerpt

Virulent and moderately virulent strains of Newcastle disease virus (NDV), representing avian paramyxovirus serotype 1 (APMV-1), cause respiratory and neurological disease in chickens and other species of birds. In contrast, APMV-2 is avirulent in chickens. We investigated the role of the fusion (F) and hemagglutinin-neuraminidase (HN) envelope glycoproteins in these contrasting phenotypes by designing chimeric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Respiratory viral infections research
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21680512
DOI: 10.1128/jvi.00652-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of the Fusion and Hemagglutinin-Neuraminidase Proteins in Replication, Tropism, and Pathogenicity of Avian ParamyxovirusesPMID 21680512Read ↗

The hemagglutinin-neuraminidase protein of Newcastle disease virus determines tropism and virulence.Semantic proximity Read ↗

Chimeric Newcastle Disease Virus Protects Chickens against Avian Influenza in the Presence of Maternally Derived NDV ImmunitySemantic proximity Read ↗

Comparative biology of two genetically closely related Newcastle disease virus strains with strongly contrasting pathogenicity.Semantic proximity Read ↗

Different Regions of the Newcastle Disease Virus Fusion Protein Modulate PathogenicitySemantic proximity Read ↗

A single amino acid substitution in the haemagglutinin-neuraminidase protein of Newcastle disease virus results in increased fusion promotion and decreased neuraminidase activities without changes in virus pathotypeSemantic proximity Read ↗

Mutations in the Cytoplasmic Domain of the Newcastle Disease Virus Fusion Protein Confer Hyperfusogenic Phenotypes Modulating Viral Replication and PathogenicitySemantic proximity Read ↗

Mutations in the Fusion Protein Cleavage Site of Avian Paramyxovirus Serotype 2 Increase Cleavability and Syncytium Formation but Do Not Increase Viral Virulence in ChickensSemantic proximity Read ↗

Newcastle disease virus fusion and haemagglutinin-neuraminidase proteins contribute to its macrophage host rangeSemantic proximity Read ↗

Mutagenesis of the di-leucine motif in the cytoplasmic tail of newcastle disease virus fusion protein modulates the viral fusion ability and pathogenesis.Semantic proximity Read ↗

The Large Polymerase Protein Is Associated with the Virulence of Newcastle Disease VirusSemantic proximity Read ↗

Coordinate Deletion of N-Glycans from the Heptad Repeats of the Fusion F Protein of Newcastle Disease Virus Yields a Hyperfusogenic Virus with Increased Replication, Virulence, and ImmunogenicitySemantic proximity Read ↗

Contribution of the length of the HN protein and the sequence of the F protein cleavage site to Newcastle disease virus pathogenicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.