Article
Sperm tail abnormalities in mutant mice with neo(r) gene insertion into an intron of the keratin 9 gene.
Molecular reproduction and development - 1 Oct 2005
Rivkin Eugene, Eddy Edward M, Willis William D, Goulding Euginia H, Suganuma Ryota, Yanagimachi Ryuzo, Kierszenbaum Abraham L
Abstract excerpt
Keratin 9 (K9) is one of the components of the perinuclear ring of the manchette found in developing spermatids but is predominantly expressed in the epidermis of the footpad (palm and sole in human epidermis). As an initial step to determine the function of K9 protein in sperm development, we have generated a mutant mouse by homologous recombination of the targeting vector containing the disrupted K9 gene in...
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