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Article

Demonstration of the pathogenic effect of point mutated keratin 9 in vivo

19 Mar 1999

Abstract excerpt

A wild type keratin 9 (K9) cDNA and a point mutated keratin 9 cDNA were injected subcutaneously into mouse skin. The hemagglutinin tag staining of the wild type K9 cDNA injected specimens mainly showed a homogeneous pattern, whereas the point mutated K9 cDNA injected specimens mainly showed a granular pattern in the suprabasal cells. Double staining of K9 and the endogenous keratin revealed the incorporation of...

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PMID: 10218578
DOI: 10.1016/s0014-5793(99)00233-1

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