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Article

Impact of missing genotype data on Monte-Carlo simulation based haplotype analysis.

Human heredity - 1 Jan 2005

Becker Tim, Knapp Michael

Abstract excerpt

In the context of haplotype association analysis of unphased genotype data, methods based on Monte-Carlo simulations are often used to compensate for missing or inappropriate asymptotic theory. Moreover, such methods are an indispensable means to deal with multiple testing problems. We want to call attention to a potential trap in this usually useful approach: The simulation approach may lead to strongly inflated...

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PMID: 16015028
DOI: 10.1159/000086696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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