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Article

A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor.

Molecular endocrinology (Baltimore, Md.) - 1 Apr 1998

Lu D, Vage D I, Cone R D

Abstract excerpt

Dark coat color in the mouse and fox results from constitutively activated melanocortin-1 receptors. Receptor mutations in the mouse (E92K, L98P), cow (L99P), fox (C125R), and sheep (D119N) cluster near the membrane/extracellular junctions of the second and third transmembrane domains, an acidic...

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Identifiers

PMID: 9544994
DOI: 10.1210/mend.12.4.0091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9544994-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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