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Article

A single targeted Ets2 allele restricts development of mammary tumors in transgenic mice.

Cancer research - 1 Sept 1999

Neznanov N, Man A K, Yamamoto H, Hauser C A, Cardiff R D, Oshima R G

Abstract excerpt

Heterozygous female mice carrying a targeted mutation of the Ets2 transcription factor gene were mated with a mouse strain that develops mammary tumors due to the expression of the polyoma virus middle T oncogene. Tumors from females with only one wild-type Ets2 gene were approximately one-half the size of tumors from controls. The smaller size of the tumors was correlated with a more differentiated state of...

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PMID: 10485465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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