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Ets2 in Tumor Fibroblasts Promotes Angiogenesis in Breast Cancer

16 Aug 2013

Abstract excerpt

Tumor fibroblasts are active partners in tumor progression, but the genes and pathways that mediate this collaboration are ill-defined. Previous work demonstrates that Ets2 function in stromal cells significantly contributes to breast tumor progression. Conditional mouse models were used to study the function of Ets2 in both mammary stromal fibroblasts and epithelial cells. Conditional inactivation of Ets2 in...

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PMID: 23977064
DOI: 10.1371/journal.pone.0071533

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