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Article

Coevolutionary Genetics of Plasmodium Malaria Parasites and Their Human Hosts

1 Apr 2002

Abstract excerpt

Malaria has been invoked, perhaps more than any other infectious disease, as a force for the selection of human genetic polymorphisms. Evidence for genome-shaping interactions can be found in the geographic and ethnic distributions of the hemoglobins, blood group antigens, thalassemias, red cell membrane molecules, human lymphocyte antigen (HLA) classes, and cytokines. Human immune responses and genetic...

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PMID: 21708733
DOI: 10.1093/icb/42.2.401

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