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Article

Assessment of the transcriptional activity of p53 improves the prediction of recurrence in superficial transitional cell carcinoma of the bladder.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2005

Dekairelle Anne-France, Tombal Bertrand, Cosyns Jean-Pierre, Gala Jean-Luc

Abstract excerpt

PURPOSE: To investigate the value of p53 functional analysis of separated alleles in yeast (FASAY) as a witness of p53/p21 pathway alteration and as a predictor of recurrence in superficial transitional cell carcinomas. EXPERIMENTAL DESIGN: p53 transcriptional activity was prospectively analyzed in 52 newly diagnosed transitional cell carcinoma using FASAY competent for the transactivation of p21 and bax...

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Share to Carcinoma, Transitional Cell
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Recurrence, Local

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Share to Survival Analysis

Share to Tumor Suppressor Protein p53

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 16000567
DOI: 10.1158/1078-0432.CCR-05-0140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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