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Article

Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular lymphoma pathogenesis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2007

Ross Charles W, Ouillette Peter D, Saddler Chris M, Shedden Kerby A, Malek Sami N

Abstract excerpt

PURPOSE: Follicular lymphoma (FL) constitutes the second most common non-Hodgkin's lymphoma in the Western world. The clinical course is variable and only in part explained by known tumor-intrinsic or -extrinsic factors. FL carries the hallmark chromosomal translocation t(14;18), deregulating the expression of Bcl-2, but this is not sufficient to explain either FL biology or clinical behavior. EXPERIMENTAL...

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Share to Chromosome Aberrations
Share to Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Dosage

Share to Genes, p53

Share to Loss of Heterozygosity

Share to Lymphoma, Follicular

Share to Oligonucleotide Array Sequence Analysis

Source

Identifiers

PMID: 17699855
DOI: 10.1158/1078-0432.CCR-07-0456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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