Article
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Biological psychiatry - 1 Jul 2005
Glaser Beate, Schumacher Johannes, Williams Hywel J, Jamra Rami Abou, Ianakiev Nikolai, Milev Radoi, Ohlraun Stephanie, Schulze Thomas G, Czerski Piotr M, Hauser Joanna, Jönsson Erick G, Sedvall Göran C, Klopp Norman, Illig Thomas, Becker Tim, Propping Peter, Williams Nigel M, Cichon Sven, Kirov George, Rietschel Marcella, Murphy Kieran C, O'Donovan Michael C, Nöthen Markus M, Owen Michael J
Abstract excerpt
BACKGROUND: It has been recently reported that a functional variant in the ZDHHC8 gene encoding a putative palmitoyltransferase directly confers susceptibility to schizophrenia in females (). METHODS: We investigated the putative risk allele (rs175174) in four schizophrenia association samples including a Bulgarian proband and parent sample (474 trios) and three case-control panels of European origin (1028...
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