The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia.

doi:10.1016/j.neulet.2005.08.019

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Article

The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia.

Neuroscience letters - 30 Dec 2005

Otani Kyohei, Ujike Hiroshi, Tanaka Yuji, Morita Yukitaka, Kishimoto Makiko, Morio Akiko, Uchida Naohiko, Nomura Akira, Kuroda Shigetoshi

Abstract excerpt

The zinc finger and DHHC domain-containing protein 8 (ZDHHC8) gene is located on chromosome 22q11, which several genome scans have provided repeated evidence for a significant linkage with bipolar disorder (BPD) and schizophrenia. A recent study revealed that a single nucleotide polymorphism (SNP), rs175174, which has potential effects on splicing, in intron 4 of the ZDHHC8 gene is associated with susceptibility...

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PMID: 16150541
DOI: 10.1016/j.neulet.2005.08.019

Genes

ZDHHC8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

Semantic proximity does not establish scientific evidence.

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Click a neighbor to travelStep 1 · 12 closest

The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia.PMID 16150541Read ↗

No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population.Semantic proximity Read ↗

Testing for genetic association between the ZDHHC8 gene locus and susceptibility to schizophrenia: An integrated analysis of multiple datasets.Semantic proximity Read ↗

No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia.Semantic proximity Read ↗

No association between the dihydropyrimidinase-related protein 2 (DRP-2) gene and bipolar disorder in humans.Semantic proximity Read ↗

Association study of bromodomain-containing 1 gene with schizophrenia in Japanese population.Semantic proximity Read ↗

ZDHHC8 as a candidate gene for schizophrenia: analysis of a putative functional intronic marker in case-control and family-based association studies.Semantic proximity Read ↗

Lack of association between MPC2 variants and schizophrenia in a replication study of Han Chinese.Semantic proximity Read ↗

No association between FOXP2 rs10447760 and schizophrenia in a replication study of the Chinese Han population.Semantic proximity Read ↗

No association between genetic polymorphisms of the NDUFS7 gene and schizophrenia in Han Chinese.Semantic proximity Read ↗

Case-control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8.Semantic proximity Read ↗

Support of association between BRD1 and both schizophrenia and bipolar affective disorder.Semantic proximity Read ↗

The FEZ1 gene shows no association to schizophrenia in Caucasian or African American populations.Semantic proximity Read ↗

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