Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of CARD15 mutations on disease activity and response to therapy in 65 pediatric Crohn patients from Saxony, Germany.

Journal of pediatric gastroenterology and nutrition - 1 Jul 2005

Roesler Joachim, Thürigen Anett, Sun Liping, Koch Rainer, Winkler Ulf, Laass Martin W, Gahr Manfred, Rösen-Wolff Angela, Henker Jobst

Abstract excerpt

OBJECTIVES: Certain genetic variants in the CARD15 gene are accompanied by an enhanced risk to develop Crohn disease with the main activity in the terminal ileum and ensuing stricturing early in life. The objective of this study was to evaluate the relation between CARD15 mutations and overall disease activity and response to therapy in pediatric patients. METHODS: 65 genomic DNA samples from such patients were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Height
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Crohn Disease

Share to Germany

Share to Intracellular Signaling Peptides and Proteins

Share to Nod2 Signaling Adaptor Protein

Share to Severity of Illness Index

Source

Identifiers

PMID: 15990626
DOI: 10.1097/01.mpg.0000165017.00562.27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of CARD15 mutations on disease activity and response to therapy in 65 pediatric Crohn patients from Saxony, Germany.PMID 15990626Read ↗

CARD15 genotype and phenotype analysis in 55 pediatric patients with Crohn disease from Saxony, Germany.Semantic proximity Read ↗

CARD15 mutations are rare in Swedish pediatric Crohn disease.Semantic proximity Read ↗

CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease.Semantic proximity Read ↗

Mutations in CARD15 and smoking confer susceptibility to Crohn's disease in the Danish population.Semantic proximity Read ↗

Influence of smoking habits and CARD15 mutations on the onset of Crohn's disease.Semantic proximity Read ↗

NOD2/CARD15 mutations in Croatian patients with Crohn's disease: prevalence and genotype-phenotype relationship.Semantic proximity Read ↗

NOD2/CARD15 variants are associated with lower weight at diagnosis in children with Crohn's disease.Semantic proximity Read ↗

CARD15 gene polymorphisms in Serbian patients with Crohn's disease: genotype-phenotype analysis.Semantic proximity Read ↗

Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: an Italian multicentric study.Semantic proximity Read ↗

NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype-phenotype analysis in Danish and Portuguese patients and controls.Semantic proximity Read ↗

Prevalence of SLC22A4, SLC22A5 and CARD15 gene mutations in Hungarian pediatric patients with Crohn's disease.Semantic proximity Read ↗

CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.