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Article

A computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries.

Nucleic acids research - 1 Jan 2005

Volles Michael J, Lansbury Peter T

Abstract excerpt

A computer program for the generation and analysis of in silico random point mutagenesis libraries is described. The program operates by mutagenizing an input nucleic acid sequence according to mutation parameters specified by the user for each sequence position and type of point mutation. The program can mimic almost any type of random mutagenesis library, including those produced via error-prone PCR (ep-PCR),...

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Identifiers

PMID: 15990391
DOI: 10.1093/nar/gki669
PMCID: PMC1166583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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