Article
Random Mutagenesis Using Error-Prone DNA Polymerases.
Cold Spring Harbor protocols - 1 Mar 2018
Forloni Matteo, Liu Alex Y, Wajapeyee Narendra
Abstract excerpt
"Random mutagenesis" is a technique that allows researchers to develop large libraries of variants of a particular DNA sequence. Once developed, these libraries can then be used for several purposes, including structure-function and directed evolution studies. Random mutagenesis is different from other mutagenesis techniques in that it does not require the researcher to have any prior knowledge about the...
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