Article
Redistribution of human immunodeficiency virus type 1 variants resistant to protease inhibitors after a protease inhibitor-sparing regimen.
AIDS research and human retroviruses - 1 Jun 2005
Gianotti Nicola, Seminari Elena, Lazzarin Adriano, Boeri Enzo, Clementi Massimo, Danise Anna, Salpietro Stefania, Fusetti Giuliana, Castagna Antonella
Abstract excerpt
The redistribution of mutations related to protease inhibitor (PI) resistance after a PI-sparing regimen in human immunodeficiency virus (HIV)-infected, highly PI-experienced patients was prospectively assessed. Twenty-five patients failing a PI-including regimen were given PI-sparing antiretroviral therapy, and then followed for 24 weeks after PI resumption. Genotyping was performed by direct sequencing before...
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