Article
Segregation analysis detects a major gene controlling blood infection levels in human malaria.
American journal of human genetics - 1 Jun 1992
Abel L, Cot M, Mulder L, Carnevale P, Feingold J
Abstract excerpt
The profound influence that the genetic makeup of the host has on resistance to malaria infection has been established in numerous animal studies. This genetic heterogeneity is one of the main causes of the difficulties in developing an effective malaria vaccine. Segregation analysis is the first step in identifying the nature of genetic factors involved in the expression of human complex diseases, as infectious...
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