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Article

Human malaria: segregation analysis of blood infection levels in a suburban area and a rural area in Burkina Faso.

Genetic epidemiology - 1 Jan 1998

Rihet P, Abel L, Traoré Y, Traoré-Leroux T, Aucan C, Fumoux F

Abstract excerpt

The genetic control of blood infection levels in human malaria remains unclear. Case control studies have not demonstrated a strong association between candidate genes and blood parasite densities as opposed to surveys that have focused on severe malaria. As an alternative approach, we used segregation analyses to determine the genetic control of blood parasitemia. We surveyed 509 residents (53 pedigrees) in a...

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PMID: 9728888
DOI: 10.1002/(SICI)1098-2272(1998)15:5<435::AID-GEPI1>3.0.CO;2-#

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