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Article

Heritability of malaria in Africa.

PLoS medicine - 1 Dec 2005

Mackinnon Margaret J, Mwangi Tabitha W, Snow Robert W, Marsh Kevin, Williams Thomas N

Abstract excerpt

BACKGROUND: While many individual genes have been identified that confer protection against malaria, the overall impact of host genetics on malarial risk remains unknown. METHODS AND FINDINGS: We have used pedigree-based genetic variance component analysis to determine the relative contributions of genetic and other factors to the variability in incidence of malaria and other infectious diseases in two cohorts of...

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Identifiers

PMID: 16259530
DOI: 10.1371/journal.pmed.0020340
PMCID: PMC1277928

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