Genetic control of blood infection levels in human malaria: evidence for a complex genetic model.

doi:10.4269/ajtmh.1998.58.480

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Article

Genetic control of blood infection levels in human malaria: evidence for a complex genetic model.

The American journal of tropical medicine and hygiene - 1 Apr 1998

Garcia A, Cot M, Chippaux J P, Ranque S, Feingold J, Demenais F, Abel L

Abstract excerpt

There is now accumulating evidence for the involvement of genetic factors in the control of immune response against malaria. These arguments come from numerous animal models, from population studies showing associations of red blood cell genetic defects as well as HLA antigens with severe malaria...

Topics

Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Alleles
Cameroon
Child
Child, Preschool
Family
Follow-Up Studies
Gene Frequency
Humans
Infant
Malaria
Middle Aged
Models, Genetic
Parasitemia

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