Article
Genetic control of blood infection levels in human malaria: evidence for a complex genetic model.
The American journal of tropical medicine and hygiene - 1 Apr 1998
Garcia A, Cot M, Chippaux J P, Ranque S, Feingold J, Demenais F, Abel L
Abstract excerpt
There is now accumulating evidence for the involvement of genetic factors in the control of immune response against malaria. These arguments come from numerous animal models, from population studies showing associations of red blood cell genetic defects as well as HLA antigens with severe malaria, and from familial studies including a recent segregation analysis, which led to detection of a major gene effect...
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