Article

Genome-wide association study and genomic risk prediction of age-related macular degeneration in Israel

2023-09-06

Abstract excerpt

<h4>Purpose</h4> The risk of developing age-related macular degeneration(AMD) is influenced by genetic background. In 2016, International AMD Genomics Consortium(IAMDGC) identified 52 risk variants in 34 loci, and a polygenic risk score(PRS) based on these variants was associated with AMD. The Israeli population has a unique genetic composition: Ashkenazi Jewish(AJ), Jewish non-Ashkenazi, and Arab sub-populations....

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Literature Corpus work: 8d441569-4f41-50a8-b558-0606c7a19692
DOI: 10.1101/2023.09.06.23295126

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