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Article

The AIB1 glutamine repeat polymorphism is not associated with risk of breast cancer before age 40 years in Australian women.

Breast cancer research : BCR - 1 Jan 2005

Montgomery Karen G, Chang Jiun-Horng, Gertig Dorota M, Dite Gillian S, McCredie Margaret R, Giles Graham G, Southey Melissa C, Hopper John L, Campbell Ian G

Abstract excerpt

INTRODUCTION: AIB1, located at 20q12, is a member of the steroid hormone coactivator family. It contains a glutamine repeat (CAG/CAA) polymorphism at its carboxyl-terminal region that may alter the transcriptional activation of the receptor and affect susceptibility to breast cancer through altered sensitivity to hormones. METHODS: We evaluated this repeat polymorphism in the context of early-onset disease by...

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Identifiers

PMID: 15987430
DOI: 10.1186/bcr1009
PMCID: PMC1143559

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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