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Article

Involvement of Inflammation, Degradation, and Apoptosis in a Mouse Model of Glaucoma

29 Jun 2005

Abstract excerpt

Glaucoma is a common cause of blindness affecting at least 66 million people worldwide. Pigmentary glaucoma is one of the most common forms of secondary glaucoma, and its pathogenesis remains unclear. Interleukin-18 (IL-18) is an important regulator of innate and acquired immune responses and plays an important role in inflammatory/autoimmunity diseases. Using the DBA/2J mouse as an animal model of human...

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PMID: 15985430
DOI: 10.1074/jbc.m502641200

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