Article

TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma

2024-06-08

Abstract excerpt

Glaucoma is a leading cause of irreversible blindness worldwide. Toll-like receptor 4 (TLR4) is a pattern-recognition transmembrane receptor that induces neuroinflammatory processes in response to injury. Tlr4 is highly expressed in ocular tissues and is known to modulate inflammatory processes in both anterior and posterior segment tissues. TLR4 activation can lead to mitochondrial dysfunction and metabolic defi...

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Literature Corpus work: ca2152cd-4a91-5323-8d46-e84d867c9302
DOI: 10.1101/2024.06.07.597951

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