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Article

Crosstalk between MicroRNA and Oxidative Stress in Primary Open-Angle Glaucoma

28 Feb 2021

Abstract excerpt

Reactive oxygen species (ROS) plays a key role in the pathogenesis of primary open-angle glaucoma (POAG), a chronic neurodegenerative disease that damages the trabecular meshwork (TM) cells, inducing apoptosis of the retinal ganglion cells (RGC), deteriorating the optic nerve head, and leading to blindness. Aqueous humor (AH) outflow resistance and intraocular pressure (IOP) elevation contribute to disease...

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PMID: 33670885
DOI: 10.3390/ijms22052421

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