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Article

Novel biosensors for the detection of estrogen receptor ligands.

The Journal of steroid biochemistry and molecular biology - 1 Aug 2005

De Siddhartha, Macara Ian G, Lannigan Deborah A

Abstract excerpt

There exists a significant need for the detection of novel estrogen receptor (ER) ligands for pharmaceutical uses, especially for treating complications associated with menopause. We have developed fluorescence resonance energy transfer (FRET)-based biosensors that permit the direct in vitro detection of ER ligands. These biosensors contain an ER ligand-binding domain (LBD) flanked by the FRET donor fluorophore,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 15985367
DOI: 10.1016/j.jsbmb.2005.04.030

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CFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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