Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ligand-binding domain of estrogen receptors.

Current opinion in biotechnology - 1 Dec 1999

Mueller-Fahrnow A, Egner U

Abstract excerpt

Estrogen receptors are multi-domain proteins that interact with other proteins and DNA to fulfil their function: the regulation of transcription. During the past 2-3 years, our understanding of this complex process has increased tremendously as crystal structures of isolated ligand-binding domains in complex with various ligands, as well as co-activator peptides, are now available. The structural information,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Dimerization
Share to Ligands

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phylogeny

Share to Protein Binding

Share to Protein Conformation

Share to Receptors, Estrogen

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 10600690
DOI: 10.1016/s0958-1669(99)00034-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ligand-binding domain of estrogen receptors.PMID 10600690Read ↗

Nuclear Hormone Receptor Coregulators In Action: Diversity For Shared TasksSemantic proximity Read ↗

Estrogen receptor and breast cancer.Semantic proximity Read ↗

Crystallographic comparison of the estrogen and progesterone receptor’s ligand binding domainsSemantic proximity Read ↗

Nuclear Receptor Minireview SeriesSemantic proximity Read ↗

Identification of Regions within the F Domain of the Human Estrogen Receptor α that Are Important for Modulating Transactivation and Protein-Protein InteractionsSemantic proximity Read ↗

Molecular determinants of the estrogen receptor-coactivator interface.Semantic proximity Read ↗

Estrogen receptors (ER<sub>α</sub>versus ER<sub>β</sub>): friends or foes in human biology?Semantic proximity Read ↗

A comprehensive structural and functional analysis of the ligand binding domain of the nuclear receptor superfamily reveals highly conserved signaling motifs and two distinct canonical forms through evolutionSemantic proximity Read ↗

New perspectives into the biological and clinical relevance of oestrogen receptors in the human breastSemantic proximity Read ↗

Role of coactivators and corepressors in steroid and nuclear receptor signaling: potential markers of tumor growth and drug sensitivity.Semantic proximity Read ↗

Steroid receptors and coregulators: Dissemination of sex differences and emerging technologiesSemantic proximity Read ↗

Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.