Article
Gold Nanoparticle-Based Förster Resonance Energy Transfer (FRET) Analysis of Estrogen Receptor: DNA Interaction.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Su Xiaodi, Aung Khin Moh Moh, Lukman Steven, Liu Bin
Abstract excerpt
Estrogen receptors play critical roles in regulating genes responsible for development and maintenance of reproductive tissues and other physiological function. The interaction of ERs with DNA sequences, known as estrogen response elements (EREs) (a palindromic repeat separated by three-base spacer, 5'GGTCAnnnTGACC-3'), is required for estrogen regulation of target gene expression. Here, we describe a simple...
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