Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product.

doi:10.1002/1521-4141(200108)31:8<2497::aid-immu2497>3.0.co;2-j

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Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product.

European journal of immunology - 1 Aug 2001

Bleul C C, Boehm T

Abstract excerpt

T cell development requires the interaction of developing thymocytes with thymic epithelial cells. Thymic epithelial cells acquire their unique phenotype under the control of the winged-helix transcription factor Whn, which is lacking in the nude mouse. Whn-dependent genes may therefore be important regulators of lympho-epithelial interactions. To identify Whn target genes we isolated RNA populations of wild-type...

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Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product.

Abstract excerpt

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Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product.

Abstract excerpt

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