Article
CYP3A5*3 polymorphism and cancer risk: a meta-analysis and meta-regression.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2013
Wang Bao-Sheng, Liu Zhen, Xu Wei-Xue, Sun Shao-Long
Abstract excerpt
CYP3A5 is a cytochrome P450 superfamily member which is involved in the metabolism of drugs, steroid hormones, and other xenobiotics. Emerging evidences suggest that CYP3A5*3 (rs776746 A>G) polymorphism may play a role in the etiology of carcinogenesis and affect an individual's susceptibility to cancer in humans, but individually published studies showed inconclusive results. This meta-analysis aimed to derive a...
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