Article
Study the polymorphism of CYP3A5 and CYP3A4 loci in Iranian population with laryngeal squamous cell carcinoma.
Molecular biology reports - 1 Nov 2011
Azarpira Negar, Ashraf Mohamad Javad, Khademi Bigan, Darai Masumeh, Hakimzadeh Afsoon, Abedi Elham
Abstract excerpt
Cancer reflects a complicated network of interactions between genes and environmental factors. Cytochrome P450 (CYP) is a multi-gene superfamily participating in the metabolism of xenobiotics. The aim of our study was to examine whether polymorphisms in the CYP enzyme genes affect the risk of developing larynx squamous cell carcinoma (SCC). Polymorphism of CYP3A5 and CYP3A4 genes were investigated in 50 patients...
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