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Article

B7-homolog 1 expression by human glioma: a new mechanism of immune evasion

1 Jul 2005

Abstract excerpt

Immunosuppressive soluble factors such as transforming growth factor beta and cell surface molecules such as FasL may contribute to the immune evasion of malignant glioma. B7 homolog 1 is a member of the B7 family of costimulatory molecules implicated in the negative regulation of T cell immune responses. Here, we show that human glioma cell lines express B7 homolog 1 protein that reduces interferon-gamma...

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PMID: 15973152
DOI: 10.1097/00001756-200507130-00010

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